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Sleep & Recovery

Melatonin

The sleep hormone for jet lag, shift work, and sleep onset

Evidence Grade: A — Strong clinical evidence Sleep & Recovery
A
Evidence Grade A: Strong clinical evidence Based on the volume and quality of published human clinical trials.

Melatonin is a hormone produced by the pineal gland that signals darkness and regulates circadian rhythm. Supplemental melatonin is most effective for circadian phase-shifting (jet lag, shift work) rather than treating chronic insomnia — where it has modest effects. The common practice of taking high doses (5–10 mg) is likely counterproductive; most research shows 0.5–1 mg is equally effective with fewer side effects.

Key Benefits

  • Jet lag recovery
  • Shift work sleep disorder
  • Sleep onset in insomnia
  • Circadian rhythm regulation
  • Antioxidant (high-dose)
  • REM sleep support

Best Form

Immediate-release for sleep onset; extended-release for sleep maintenance; sublingual for fastest effect

Dosage

0.5–1 mg for circadian use; 1–5 mg for insomnia (lower doses often equally effective)

⚠ Safety Notes

Generally safe short-term. Long-term use may suppress endogenous production. Morning grogginess is common with doses above 1 mg. Not suitable for children without medical supervision.

This page is for educational purposes only. Consult a healthcare professional before starting any supplement.